Glossary

The average number of bleeds someone has in a year. This is the measurement most commonly used to evaluate hemophilia treatments.

Anticoagulants, which are proteins that prevent clotting. Ex: tissue factor pathway inhibitor (TFPI)

Protein in blood that promotes blood clotting, also known as procoagulant. You may see one represented with a capital F and Roman numeral. Ex: low levels of FVIII or FIX can determine a hemophilia diagnosis and severity

A non-factor based treatment that restores the balance of clotting and anti-clotting factors in the blood to improve clotting

A single joint that has had 3 or more spontaneous bleeds within a 6-month period

A protein in the body that works in a key phase of clotting

A key anticlotting factor that prevents clotting